|
MedChemExpress
dht igf1 ![]() Dht Igf1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/dht+igf1/IGF-I%2FIGF-1%2C+Human/pmc13170201-194-30-36 Average 95 stars, based on 1 article reviews
dht igf1 - by Bioz Stars,
2026-10
95/100 stars
|
Buy from Supplier |
Image Search Results
Journal: Advanced Science
Article Title: IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome
doi: 10.1002/advs.202520455
Figure Lengend Snippet: IGFBP5 supplementation improves endometrial receptivity in PCOS‐derived endometrium. (A) Relative expression of IGFBP5 in proliferative and secretory endometrium of control women, n = 8 per group; (B) Representative immunohistochemistry staining of IGFBP5 in human endometrium of proliferative and secretory phase of control women, scale bars: 50 µm; (C) Quantitative analysis of IGFBP5 protein levels in epithelial and stromal cells of proliferative and secretory endometrium of control women, n = 3 per group; (D) Relative expression of IGFBP5 in secretory endometrium from the CON and PCOS groups, n = 8 per group; (E‐F) Representative immunohistochemistry staining (E) and its quantitative analysis (F) of IGFBP5 protein levels in the secretory endometrium from the CON and PCOS groups, n = 6 per group, scale bars: 50 µm; (G) IGFBP5 mRNA levels in DHT‐treated Ishikawa cells, n = 3 per group; (H) The percentage of JAr spheroids that adhere to Ishikawa cells treated with DHT (0.5 µM), DHT + IGFBP5 (100 ng/ml), DHT + IGF1 (50 ng/ml), DHT + IGFBP5 + IGF1 and DHT + IGFBP5 + NVP‐AEW541 (10 µM), n = 3 per group. For A, C, D, F, G, and H, data are presented as mean ± SEM. For A, C, D, and F, the P value was determined by a two‐tailed Student's t ‐test; for G and H, the P value was determined by one‐way ANOVA with Tukey's multiple comparison post hoc test. For B and E, the experiments were performed in three replicates; le, luminal epithelium; ge, glandular epithelium; s, stroma.
Article Snippet: Before co‐cultured with JAr spheroids, Ishikawa cells were primed under serum‐free conditions for 24 h with DHT (0.5 μM), DHT + IGFBP5 (100 ng/mL, HY‐ P72378 , Med Chem Express),
Techniques: Derivative Assay, Expressing, Control, Immunohistochemistry, Staining, Two Tailed Test, Comparison